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neuron,hepatoblast,cardiomyocyte etc. Gene therapyin vivo cistron therapyex vivo sequence therapyreplacement of lacking cistron victimization either:retrovirus (inserts into organization genome)ordna microorganism (directly univocal gene)bonemarrowculture in vitroretroviruscontaininggene ofinterestinfectioninject into topographic point tissue(muscle, osseous tissue marrow)problems:viral oncogenesisimmune responseinject intotarget organfig.
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